New technology may pave the way for development of point-of-care devices and diagnostic tests

New short-course treatment effective against HIV-associated cryptococcal meningitis

Biomarkers are components that may be present in biological samples and are related to specific diseases. Therefore, doctors can analyze biological samples from a patient to check their health condition or to monitor the progress of a specific therapy. Typically, these samples need to be purified and diluted before the analysis, and current medical diagnostic … Read more

The answer to stopping the coronavirus may be up the nose

The answer to stopping the coronavirus may be up the nose

Tea Covid-19 vaccines authorized for use today were developed at unprecedented speed and surpassed expectations in how well they worked. The billions of people who are protected by them have avoided severe symptoms, hospitalization and deaths. These vaccines are a scientific success beyond measure. And yet they could be even better. The enemy has evolved, … Read more

How has COVID-19 affected maternal mental health?

Study: Uncovering the collateral impacts of COVID-19 on maternal mental health. Image Credit: fizkes / Shutterstock

The ongoing pandemic of coronavirus disease 2019 (COVID-19) has caused severe disruption of social and economic interactions, affecting health services and other important aspects of human life. Until the onset of the Omicron (B.1.1.529) wave, COVID-19 had already had a staggering impact on the world, with over 40% of the world’s population already infected once … Read more

What role do children play in household transmission of COVID-19?

Study: The Role of Children in Household Transmission of COVID-19: A Systematic Review and Meta-Analysis. Image Credit: Halfpoint / Shutterstock

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the coronavirus disease 2019 (COVID-19) pandemic and has claimed more than 6.26 million lives. Households represent a high-risk exposure setting for SARS-CoV-2 transmission, and the role of children in spreading the virus is not known. A new study published in the … Read more

Experts attribute Victoria’s COVID-19 rate rise to change in weather, waning immunity

A healthcare worker prepares a vaccine at a hub in Melbourne.

As Victorians emerged from two years largely defined by lockdowns, the start of 2022 was marked by the sharp rise and fall of cases as a wave of Omicron swept through. That wave, which peaked in early January with tens of thousands of cases per day, subsided somewhat, but epidemiologists warned there would be more … Read more

Direct infection and replication of influenza virus in cardiomyocytes is a primary determinant of cardiac pathology associated with severe influenza

Study: Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis. Image Credit: pinkeyes/Shutterstock

In a recent study published in Science Advances, researchers generated a recombinant influenza virus expressing micro ribonucleic acid (miRNAs) expressed in cardiomyocytes to infect mice, which served as a model to study the etiology of influenza-associated cardiac pathology. Study: Influenza virus replication in cardiomyocytes drives heart dysfunction and fibrosis. Image Credit: pinkeyes/Shutterstock Background Several studies … Read more

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

Study: Short-lived booster effect and stable CD8+ T cell memory after 3rd COVID-19 vaccine dose. Image Credit: KT Stock photos/Shutterstock

Since the initial global outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, a continuous evolution of the virus has been observed. The emergence of new SARS-CoV-2 variants, which have been classified as variants of concern (VOC) and variants of interest (VOI), has reduced the efficacy … Read more

Nanotech imaging device shows potential to make disease diagnosis with smartphones

New method for generating lung tissue from just a few body cells in the lab

A nanotech imaging device, tiny enough to fit on a smartphone camera lens, has the potential to make the diagnosis of certain diseases accessible and affordable for people in rural and remote regions, say Australian scientists who developed it. The COVID-19 pandemic has brought diagnostics into sharp focus and the World Health Organization has called … Read more

SARS-CoV-2 Omicron escapes immune response due to high ACE2 affinity and low antibody specificity

Study: Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron. ​​​​​​​Image Credit: Orpheus FX / Shutterstock

In a recent study published in the journal Vaccinesresearchers revealed how severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron escapes neutralizing antibodies (nAbs). Two days after it was first reported on November 24, 2021, the World Health Organization (WHO) designated SARS-CoV-2 Omicron as a variant of concern (VOC). The WHO estimated a potentially higher risk of … Read more

Elevated and sustained autoantibodies following COVID-19

Study: Longitudinal analysis reveals elevation then sustained higher expression of autoantibodies for six months after SARS-CoV-2 infection. Image Credit:  Corona Borealis Studio/Shutterstock

A recent study posted to the medRxiv* preprint server demonstrated that autoantibody levels rise following acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and remain to be elevated for about six months. Study: Longitudinal analysis reveals elevation then sustained higher expression of autoantibodies for six months after SARS-CoV-2 infection. Image Credit: Corona Borealis Studio/Shutterstock … Read more