Natural immunity weak and short-lived in unvaccinated after Omicron infection

Study: Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. Image Credit: Naeblys / Shutterstock

In a recent study posted to the journal Natureresearchers showed that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron infection without SARS-CoV-2 vaccination conferred poor cross-variant neutralizing capacities. Study: Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination. Image Credit: Naeblys/Shutterstock Background Numerous waves of infection have occurred since the start of the CoV disease … Read more

SARS-CoV-2 Omicron linked to rise in croup in young children

Study: COVID-19–Associated Croup in Children. Image Credit: VGstockstudio / Shutterstock.com

A recent Pediatrics study assesses the causative relationship between the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and croup or “barking cough” in children. Study: COVID-19–Associated Croup in Children. Image Credit: VGstockstudio / Shutterstock.com Coronaviruses and croup Throughout the entire duration of the coronavirus disease 2019 (COVID-19) pandemic, the causative SARS-CoV-2 has evolved. The … Read more

Evaluating SARS-CoV-2 infection risk in indoor environments

Study: Transmissibility of coronavirus and its variants from infected subjects in indoor environments. Image Credit: Elizaveta Galitckaia / Shutterstock

In a recent study under review at the Scientific Reports journal and posted to the Research Square* preprint server, researchers evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection risk for indoor scenarios. Study: Transmissibility of coronavirus and its variants from infected subjects in indoor environments. Image Credit: Elizaveta Galitckaia / Shutterstock Background Apart from … Read more

How has COVID-19 affected maternal mental health?

Study: Uncovering the collateral impacts of COVID-19 on maternal mental health. Image Credit: fizkes / Shutterstock

The ongoing pandemic of coronavirus disease 2019 (COVID-19) has caused severe disruption of social and economic interactions, affecting health services and other important aspects of human life. Until the onset of the Omicron (B.1.1.529) wave, COVID-19 had already had a staggering impact on the world, with over 40% of the world’s population already infected once … Read more

What role do children play in household transmission of COVID-19?

Study: The Role of Children in Household Transmission of COVID-19: A Systematic Review and Meta-Analysis. Image Credit: Halfpoint / Shutterstock

The global outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in the coronavirus disease 2019 (COVID-19) pandemic and has claimed more than 6.26 million lives. Households represent a high-risk exposure setting for SARS-CoV-2 transmission, and the role of children in spreading the virus is not known. A new study published in the … Read more

Experts attribute Victoria’s COVID-19 rate rise to change in weather, waning immunity

A healthcare worker prepares a vaccine at a hub in Melbourne.

As Victorians emerged from two years largely defined by lockdowns, the start of 2022 was marked by the sharp rise and fall of cases as a wave of Omicron swept through. That wave, which peaked in early January with tens of thousands of cases per day, subsided somewhat, but epidemiologists warned there would be more … Read more

Artificial proteins as specific and versatile neutralizing binders targeting the spike of SARS-CoV-2

Study: Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals. Image Credit: Naeblys/Shutterstock

In a recent article posted to the bioRxiv* preprint server, researchers demonstrated that the biosynthetic proteins called αReps addressing the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein could be novel SARS-CoV-2 antivirals Study: Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals. Image Credit: Naeblys/Shutterstock Background The CoV disease 2019 (COVID-19) catastrophe, which … Read more

Exploring short-term effectiveness of COVID-19 booster vaccine and stable CD8+ T cell memory after three doses

Study: Short-lived booster effect and stable CD8+ T cell memory after 3rd COVID-19 vaccine dose. Image Credit: KT Stock photos/Shutterstock

Since the initial global outbreak of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), the causal agent of the coronavirus disease 2019 (COVID-19) pandemic, a continuous evolution of the virus has been observed. The emergence of new SARS-CoV-2 variants, which have been classified as variants of concern (VOC) and variants of interest (VOI), has reduced the efficacy … Read more

Bayesian viral allele selection for SARS-CoV-2 genomic surveillance

Study: Inferring selection effects in SARS-CoV-2 with Bayesian Viral Allele Selection. Image Credit: NIAID

In a recent study posted to the bioRxiv* preprint server, researchers assessed the selection effects in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using Bayesian viral allele selection. Various studies have reported novel SARS-CoV-2 mutations that have been associated with increased transmissibility, increased binding to angiotensin-converting enzyme 2 (ACE2), and antibody evasion. However, the functional … Read more

SARS-CoV-2 Omicron escapes immune response due to high ACE2 affinity and low antibody specificity

Study: Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron. ​​​​​​​Image Credit: Orpheus FX / Shutterstock

In a recent study published in the journal Vaccinesresearchers revealed how severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron escapes neutralizing antibodies (nAbs). Two days after it was first reported on November 24, 2021, the World Health Organization (WHO) designated SARS-CoV-2 Omicron as a variant of concern (VOC). The WHO estimated a potentially higher risk of … Read more