SARS-CoV-2 Omicron escapes immune response due to high ACE2 affinity and low antibody specificity

Study: Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron. ​​​​​​​Image Credit: Orpheus FX / Shutterstock

In a recent study published in the journal Vaccinesresearchers revealed how severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) Omicron escapes neutralizing antibodies (nAbs). Two days after it was first reported on November 24, 2021, the World Health Organization (WHO) designated SARS-CoV-2 Omicron as a variant of concern (VOC). The WHO estimated a potentially higher risk of … Read more

Researchers reveal the mechanism of action of century-old BCG vaccine

Booster doses provide strong protection against hospitalization and death from COVID-19

The century-old Bacille Calmette-Guérin (BCG) vaccine against tuberculosis is one of the world’s oldest and most widely used vaccines, used to immunize 100 million newborns every year. Given in countries with endemic TB, it has surprisingly been found to protect newborns and young infants against multiple bacterial and viral infections unrelated to TB. There’s even … Read more

Queensland authorities warn about ‘life-threatening’ risk of catching both COVID-19 and the flu

Yvette D'Ath in a white singlet smiling as she gets a needle.

More than a dozen Queenslanders have already been hit with the double whammy of COVID-19 and flu virus infections in the past three weeks, most of them needing to be hospitalised. Key points: Authorities are expecting a big flu season this year, with immunity in the community low More than 800 flu cases have already … Read more

The generation of SARS-CoV-2 virus-like particles in insect cells

Study: SARS-CoV-2 Virus-like Particles Produced by a Single Recombinant Baculovirus Generate Anti-S Antibody and Protect against Variant Challenge. Image Credit: creativeneko/Shutterstock

The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), resulting in the COVID-19 pandemic, has pushed the world towards developing rushed but effective vaccines against the disease. Most currently employed COVID-19 vaccines rely on the principle of virus inactivation, adenoviral vectors, or the use of direct nucleic acids (mRNA/DNA). Study: SARS-CoV-2 Virus-like Particles … Read more

Is COVID-19 more dangerous than driving? How scientists are parsing coronavirus risks.

Is COVID-19 more dangerous than driving?  How scientists are parsing coronavirus risks.

Like it or not, the choose-your-own-adventure period of the pandemic is upon us. Mask mandates have fallen. Some free testing sites have closed. Whatever parts of the United States were still trying to collectively quell the pandemic have largely turned their focus away from communitywide advice. Now, even as case numbers begin to climb again … Read more

Is COVID-19 more dangerous than driving? How scientists are parsing coronavirus risks.

Is COVID-19 more dangerous than driving?  How scientists are parsing coronavirus risks.

Like it or not, the choose-your-own-adventure period of the pandemic is upon us. Mask mandates have fallen. Some free testing sites have closed. Whatever parts of the United States were still trying to collectively quell the pandemic have largely turned their focus away from communitywide advice. Now, even as case numbers begin to climb again … Read more

Single-dose vaccine delivers protection against cervical cancer-causing HPV comparable to 2 or 3-dose regimens

Study: One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer. Image Credit: ravipat/Shutterstock

A recent report published in the World Health Organization (WHO) News Release suggested that a single dose of the human papillomavirus (HPV) vaccination confers equivalent immunity to a two-dose schedule against cervical cancers caused by HPV. Study: One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer. Image Credit: ravipat/Shutterstock Background The WHO Strategic … Read more

Pfizer offers $100m to buy Brisbane company behind smartphone app that diagnoses COVID-19

A smartphone being held in a child's hand with a blue cough screening application open, green lawn in background

Pfizer has offered $100 million to buy a Brisbane-based company that has invented a smartphone app it says can diagnose COVID-19 by listening to someone cough. Key points: The company says the app has a 92 per cent success rate when diagnosing COVID-19 ResApp described the $100 million offer from Pfizer as “a game changer” … Read more

New COVID-19 variant Deltacron has been detected in Australia, here’s what we know

New COVID-19 variant Deltacron has been detected in Australia, here's what we know

A new variant of COVID-19 has been detected in Australia, which is a hybrid of two previous strains. Deltacron has been described as a mixture of the Delta variant, which spread through Australia last year, and the Omicron variant, which led to high case loads across the nation over the Christmas holidays and into this … Read more

Improved seroprevalence and antibody response after third COVID-19 vaccination

Study: Increased seroprevalence and improved antibody responses following third primary SARS-CoV-2 immunisation: an update from the COV-AD study. Image Credit: BaLL LunLa/Shutterstock

In a recent study posted to Research Square* preprint server, researchers evaluated the immunogenicity of a third coronavirus disease 2019 (COVID-19) vaccination in antibody deficient subjects. Study: Increased seroprevalence and improved antibody responses following third primary SARS-CoV-2 immunization: an update from the COV-AD study. Image Credit: BaLL LunLa/Shutterstock Background Studies have reported that the antibody … Read more