Associations between mucosal gene expression and microbiome composition in three gastrointestinal disorders

Study: Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration. Image Credit: Alpha Tauri 3D Graphics/Shutterstock

A new study authored by Sambhawa Priya and other researchers offers a detailed look at the interactions between the gut microbiome of humans in health and disease. Many chronic conditions are linked to a range of alterations in the composition of gut microflora, as well as to changes in the regulation of host genes and … Read more

Incidence of arterial and venous thromboembolism and death in COVID-19 patients

Study: Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study. Image Credit: MattLphotography/Shutterstock

In a recent study published in Infectious Diseasesresearchers estimated the incidence of arterial or venous thrombosis in patients with coronavirus disease 2019 (COVID-19). Study: Venous or arterial thrombosis and deaths among COVID-19 cases: a European network cohort study. Image Credit: MattLphotography/Shutterstock Background COVID-19 could cause arterial/venous thromboembolism due to inflammation, activation of platelets, endothelial dysfunction, … Read more

Mind-altering parasite may make people more attractive, study finds

A disease-causing parasite known to cause psychiatric symptoms such as hallucinations can make infected people more attractive, a study shows.  Here shows composite images of 10 toxoplasma-infected women and 10 Toxoplasma-infected men (a), and 10 non-infected women and ten non-infected men (b)

While disease usually may make us worse for wear, one cunning parasite makes its human carriers more physically desirable, a new study claims. In experiments, volunteers looked at photos of people who had and hadn’t been infected with Toxoplasma gondii, the parasite that causes the disease toxoplasmosis. The parasite spreads through exposure to infected cat … Read more

COVID-19 mortality strongly predicted by autoimmunity to type I interferons and advancing age

Study: The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies. Image Credit: NIAID

In a recent study published in the journal PNAS, researchers estimated the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) and relative risk of death (RRD) among subjects across ages. Study participants were either carriers of autoantibodies (auto-Abs) which neutralized low concentrations (100 pg/mL), or high concentrations (10 ng/mL) of type I … Read more

Monkeypox virus: Australian authorities on alert amid outbreak in UK, US, Europe

Monkeypox virus: Australian authorities on alert amid outbreak in UK, US, Europe

Australian experts say the spread of monkeypox virus in the US, UK and Europe “at the same time” is a “big problem” and that the disease is “not pleasant”. Australian health authorities are concerned that the rare but potentially serious monkeypox virus could reach Australia as cases are detected in the UK, the US, Canada … Read more

How does diet affect COVID-19?

Study: Do Diet and Dietary Supplements Mitigate Clinical Outcomes in COVID-19? Image Credit: New Africa / Shutterstock.com

The coronavirus disease 2019 (COVID-19) is a respiratory disease with a strong inflammatory component known as the cytokine storm that often occurs in individuals with severe disease. While many researchers are currently investigating treatments to prevent the cytokine storm, variations in diet can also significantly alter the risk of inflammation. In a recent Nutrients study, … Read more

Evaluating efficacy of SARS-CoV-2 antivirals in a mouse model

Study: A SCID mouse model to evaluate the efficacy of antivirals against SARS-CoV-2 infection. Image Credit: Kateryna Kon / Shutterstock

In a recent study posted to the bioRxiv* pre-print server, researchers from Belgium evaluated the efficacy of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antiviral drugs in a severe combined immunodeficient (SCID) mouse model. Study: A SCID mouse model to evaluate the efficacy of antivirals against SARS-CoV-2 infection. Image Credit: Kateryna Kon/Shutterstock Background Due to … Read more

Explainer: What is monkeypox and why are cases on the rise in Europe?

Explainer: What is monkeypox and why are cases on the rise in Europe?

A handful of cases of monkeypox have now been reported or are suspected in Europe and the United States. Portugal has logged five confirmed cases, and Spain is testing 23 potential cases. Neither country has reported cases before. The United Kingdom has reported nine cases and now, in the United States, the Massachusetts Department of … Read more